May 1, `02: Simon Schultz, CNS

Title: Studying the information content of spike trains

In recent years I and a number of colleagues have pushed an approach for studying spike train structure which involves breaking the Shannon information content of the spike train down into components according to the order of correlation present. This has made it feasible to examine temporal, correlational and rate coding mechanisms within a single mathematical framework. In this talk I will give an overview of our approach, and discuss how it relates to other similar attempts in the literature, dating back to the reconstruction filters used by Bialek and colleagues over 10 years ago. After explaining some of the practical issues relating to implementation of our algorithm, I will describe the results we have obtained by applying this approach to experimental data from the rat barrel cortex, from primate visual cortex, and to a model of the thalamocortical relay system.

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