Asohan Amarasingham (Brown), 12/17/03

Title: Statistical methods for assessing temporal structure in the activity of the nervous system

Abstract: One of the familiar controversies in neuroscience is the rate vs temporal coding controvery concerning how spike trains encode information: particularly, whether all that matters are the spike counts (or rate of spiking) in coarse time intervals, or whether the detailed positions of the spikes conveys information. I will discuss some statistical issues this controversy raises and techniques we have developed to address them, in particular focusing on the assessment of significance of synchronous discharges among simultaneously-recorded neurons, with experimental applications.