publications >


The temporal dynamics of cortical normalization models of decision-making

LoFaro T, Louie K, Webb R, Glimcher PW
Lett Biomath, 1: 209-220 (2014)

Normalization is a widespread neural computation in both early sensory coding and higher-order processes such as attention and multisensory integration.  It has been shown that during decision-making, normalization implements a context-dependent value code in parietal cortex.  In this paper we develop a simple differential equations model based on presumed neural circuitry that implements normalization at equilibrium and predicts specific time-varying properties of value coding.  Moreover, we show that when parameters representing value are changed, the solution curves change in a manner consistent with normalization theory and experiment.  We show that these dynamic normalization models naturally implement a time-discounted normalization over past activity, implying an intrinsic reference-dependence in value coding of a kind seen experimentally.  These results suggest that a single network mechanism can explain transient and sustained decision activity, reference dependence through time discounting, and hence emphasizes the importance of a dynamic rather than static view of divisive normalization in neural coding.

PDF