PSYCH-GA.2211 / NEURL-GA.2201, Fall Semester 2025

Mathematical Tools for Neural and Cognitive Science

Instructors: Mike Landy  &  Eero Simoncelli
Teaching Assistants: Isabel Garon    (isabelgaron AT nyu DOT edu)
Luhe Li    (luhe.li AT nyu DOT edu)
Timothy Ma    (timothy.ma AT nyu DOT edu)
Time: Lectures: Tuesday/Thursday, 10:00-12:00
Labs: selected Fridays, 9:30-12:00
Location: Lectures: Meyer 636
Labs: Meyer 636
TA Office hours: Meyer 635
Tuesday/Thursday, 2:00-3:00

Description: A graduate lecture course covering fundamental mathematical methods for analysis, modeling, and visualization of neural and cognitive data and systems. The course was introduced in Spring of 1999, became a requirement for Neural Science doctoral students in 2000, and for Psychology doctoral students in the Cognition and Perception track in 2008. The course covers a foundational set of mathematical and statistical tools, providing assumptions, motivation, logical and geometric intuition, and simple derivations for each. Concepts are reinforced with extensive computational exercises. The goal is for students to be able to understand, use and interpret these tools.

Topics include: Linear algebra, least-squares and total-least-squares regression, eigen-analysis and PCA, linear shift-invariant systems, convolution, Fourier transforms, Nyquist sampling, basics of probability and statistics, hypothesis testing, model comparison, bootstrapping, estimation and decision theory, signal detection theory, linear discriminants, classification, clustering, simple models of neural spike generation, reverse-correlation analysis.

Prerequisites: Algebra, trigonometry, and calculus. Some experience with matrix algebra and/or computer programming is helpful, but not required. The real prerequisites are an aptitude for logical and geometric reasoning, and a willingness to work hard!

Announcements: We use brightspace for class announcements and online questions/discussions: https://brightspace.nyu.edu/d2l/home/499154 . Rather than emailing the instructors or TAs, we encourage you to post your questions/comments there, where they can be discussed and/or answered by any of us or your fellow classmates.

Schedule:   (Notes: labs are in green, content will appear incrementally, for a preview see last year's course page)

Date Topic Handouts Homework
Tue, Sep 2 Introduction to the course
Linear algebra I: vectors, operations, vector spaces
Zoom recording, whiteboard (pdf)
Course description (pdf)
Slides: Linear algebra (pdf)
Notes: Linear Algebra (pdf)
 
Thu, Sep 4 Linear algebra II: inner products, projection, coordinate systems
Zoom recording, whiteboard (pdf)
Fri, Sep 5 Lab: linear algebra basics in matlab/python. Homework preparation
Lab1 (zip) - includes matlab and python
Tue, Sep 9 Linear algebra III: linear systems, matrix multiplication
Zoom recording, whiteboard (pdf)
 
Thu, Sep 11 Linear algebra IV: orthogonal/diagonal matrices, singular value decomposition
Zoom recording, whiteboard (pdf)
Homework 1 (pdf due 9/25)
Submission Instructions
Fri, Sep 12 [no lab]
Tue, Sep 16 Extended example: Color vision and trichromacy
Zoom recording, whiteboard (pdf)
Slides: Color vision and trichromacy (pdf)  
Thu, Sep 18 Regression I: regression, multiple regression via linear algebra, partitioning variance
Fri, Sep 19 Lab: linear regression

Resources (electrons):

Resources (dead trees):

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