NEURL-UA 305 (Undergraduate course ID)
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Development &
Dysfunction of the Nervous System |
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SPRING 2015 |
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(revised 9 January 2015) |
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Faculty |
Teaching Assistant |
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Dan Sanes |
Catherine Woods |
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1009 Meyer |
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212-998-3924 |
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catherine.woods@gmail.com |
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Office hours: after class or by appointment |
Office hours: after class or by appointment |
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Schedule |
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LECTURES |
Tuesday |
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11:00 a.m. - 1:30 p.m. |
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Meyer 815 |
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Readings |
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Assigned: |
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(1) Development of the
Nervous System, Third Edition (Academic Press, 2012) |
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DH Sanes, TA Reh, WA Harris |
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(2) PDF files of primary
research and review articles will be posted on NYU Classes |
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Supplemental: |
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(1) Developmental Biology,
Ninth Edition (2010) Sinauer Associates,
Gilbert SF |
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(2) Neurobiology of
Disease (2007) Elsevier Academic Press, Gilman S |
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(3) Diseases of the
Nervous System in Childhood (1992) Mac Keith Press, Aicardi
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Midterm
Exam
The midterm exam will be comprised of short-answer and short essay
questions.
The
midterm exam will be a take-home exam, available on NYU Classes March
10, and due by 11:00 p.m. March 13.
Students may NOT
work together when taking the midterm exam.
Journal
Club Presentation
Each student will present a contemporary research article for
class discussion. However, the first two sessions will be set aside to hear
Journal Club presentations by Dan Sanes and Catherine Woods, and to obtain
advice and direction on selecting a paper and preparing the presentation. These
presentation will be about 15 minutes.
Student
Lecture
Each student will deliver a presentation on a developmental
disorder that covers the human condition (phenotype, etiology, prevalence), and
research conducted with on one animal model. The presentation should be in
PowerPoint (or PDF or Keynote) format, and must not exceed 20 minutes.
Questions will be encouraged and accepted throughout the presentation. You will
be able to submit a preliminary version of your presentation and get feedback
from Dan and Catherine.
Students may NOT
work together when preparing their lectures, but may deliver the lectures to
one another for feedback on the format.
Grading
The final grade will be determined from your performance on the
following assignments:
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10% |
Class participation |
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20% |
Journal club presentation |
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30% |
Midterm exam |
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40% |
Lecture |
Attendance
Attendance is compulsory. If you miss a class without a legitimate
excuse, then the highest grade that you can obtain for the course is a B+. If
you miss two classes without a legitimate excuse, then the highest grade that
you can obtain for the course is a B. And so forth.
Schedule of Lectures & Recitations
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DATE |
TOPIC |
READINGS |
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Nervous System
Development |
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Jan 27 |
Lecture: Behavioral
development |
Chapter 10: pgs 302-325 |
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Journal Club (Dan) Discussion on selecting a research paper for Journal Club |
Assigned: Harlow and
Zimmerman (1959) Optional: Blair (2013);
Kahn (2012) PDF files at NYU Classes |
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Feb 3 |
Lecture: Early
Development of the CNS: Birth & Migration |
Chapter 2: pgs 23-32 Chapter 3: pgs 49-64 |
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Journal Club (Catherine) Discussion on preparing your Journal Club presentation |
Assigned: Wichterle et al. (2001) PDF file at NYU Classes |
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Feb 10 |
Lecture: Growth
Cones & Pathfinding |
Chapter 5 |
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Journal Club (Student presentations) |
Assigned: to be announced PDF files at NYU Classes |
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Feb
17 |
Lecture: Target
Recognition & Topographic Maps |
Chapter 6 |
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Journal Club (Student presentations) |
Assigned: to be announced PDF files at NYU Classes |
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Feb 24 |
Lecture: Catherine Woods, TBD
(Dan out-of-town) |
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Journal Club (Student presentations) |
Assigned: to be announced PDF files at NYU Classes |
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Mar 3 |
Lecture: Naturally
Occurring Neuron Cell Death |
Chapters 7 |
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Journal Club (Student presentations) |
Assigned: to be announced PDF files at NYU Classes |
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Mar 10 |
Lecture: Synapse
Formation & Plasticity |
Chapters 8-9 |
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Journal Club (Student presentations) |
Assigned: to be announced PDF files (NYU Classes) |
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Take home exam available online. Due by 11 p.m. on March 13 |
PDF file at NYU Classes |
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(Spring Break:
March 15 - 23) |
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Developmental
Disorders |
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Mar 24 |
Lecture: Cerebral
Palsy |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Mar 31 |
Lecture: Fetal
alcohol syndrome |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Apr 7 |
Lecture:
Traumatic Brain Injury & Axon Regeneration |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Apr
14 |
Lecture:
Attention Deficit Hyperactivity Disorder |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Apr 21 |
Lecture: Autism
& Williams Syndrome |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Apr 28 |
Lecture:
Schizophrenia |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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May 5 |
Lecture:
Developmental Hearing Loss |
PDF files at NYU Classes |
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Student Lectures |
PDF files at NYU Classes |
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Final Exam Week:
May 13 - 19 |
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NO FINAL EXAM |
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