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G80/G83.2201 |
Cellular, Molecular
& Developmental Neural Science |
Fall 2005 |
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Syllabus |
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(revised 6 December 2005) |
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The
class meets in Room 815 Meyer Hall, Tuesdays and Thursdays 9:00-10:45am.
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Sep 6 |
Lect 1 |
Nerves and glia: Structure of the
Nervous System |
AOKI |
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Sep 8 |
Lect 2 |
Ultrastructure of neurons &
supporting cells |
AOKI |
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Sep 13 |
Lect 3 |
Glial cells & regulation of
extracellular space PowerPoint
Slides: Glia |
CHESLER |
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Sep 15 |
Lect 4 |
Membrane biophysics I: Thermodynamic
principles PowerPoint
Slides: |
TRANCHINA |
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Sep 19 3:30pm |
Lect 5 |
Membrane biophysics II: Passive
membrane properties PowerPoint
Slides: |
TRANCHINA |
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Sep 22 |
Lect 6 |
Membrane biophysics III:
Hodgkin-Huxley model |
TRANCHINA |
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Sep 27 |
Lect 7 |
Firing patterns I: Sodium and Calcium
Channels PowerPoint
Slides: Na_&_Ca
Channels |
KOTAK |
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Sep 29 |
Lect 8 |
Firing patterns II: Potassium
channel diversity Readings: Fain, Ch 7; Hille, Ch 5; Coetzee_1999; Rudy_2001 PowerPoint
Slides: Potassium |
RUDY |
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Oct 3 3:30pm |
Lect 9 |
Synaptic transmission I: Quantal
hypothesis Readings: PowerPoint
Slides: |
TRANCHINA |
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Oct 6 |
Lect 10 |
Synaptic transmission II:
Glutamatergic systems |
AOKI |
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Oct 11 |
Lect 11 |
Synaptic transmission II: Receptor
trafficking Readings: Barry
and Ziff; Shi
et al |
ZIFF |
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Oct 13 |
Lect 12 |
Synaptic transmission III: Excitatory
synaptic plasticity Readings: Fain, Ch. 8 |
KOTAK |
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Oct 18 |
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Midterm_CMD_05.doc
is due by 10:45am |
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Oct 20 |
Lect 13 |
Synaptic transmission IV: Inhibitory
synapse function & plasticity |
SANES |
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Oct 25 |
Lect 14 |
Neuromodulators I: Dopamine &
Extrasynaptic Communication |
RICE |
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Oct 27 |
Lect 15 |
Molecular genetic approaches I:
Learning in flies and mice |
TULLY |
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Nov 1 |
Lect 16 |
Neuromodulators II: Noradrenaline TERM PAPER
OULINE DUE |
AOKI |
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Nov 3 |
Lect 17 |
Neuromodulators IV: Acetylcholine Readings: Feldman et al., Ch 7 |
AOKI |
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Nov 8 |
Lect 18 |
Molecular genetic approaches II:
Circadian rhythms in flies |
BLAU |
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Nov 10 |
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No Class - Society
for Neuroscience Meeting |
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Nov 15 |
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No Class -
Society for Neuroscience Meeting |
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Nov 17 |
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No class |
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Nov 22 |
Lect 19 |
Development I: Determination TERM PAPER DUE
(SUBMIT BY EMAIL) |
DESPLAN |
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Nov 24 |
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Thanksgiving
Holiday |
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Nov 29 |
Lect 20 |
Development II: Drosophila eye
development |
DESPLAN |
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Dec 1 |
Lect 21 |
Development III: Growth factors &
survival Power Point
Slides: Cell_Death |
SANES |
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Dec 6 |
Lect 22 |
Development IV: Axon guidance &
maps Power Point
Slides: Paths&Maps |
SANES |
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Dec 8 |
Lect 23 |
Development V: Synapse formation Power Point
Slides: Synaptogenesis |
SANES |
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Dec 13 |
Lect 24 |
Development VI: Plasticity Power Point
Slides: Plasticity
Due Mon, Dec 19,
5:00 pm (no exceptions
without permission) |
SANES |
FACULTY
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Chiye Aoki, CNS, 1056A Meyer, 8-3929, chiye@cns.nyu.edu |
Bernardo Rudy, NYUSoM, rudyb01@endeavor.med.nyu.edu |
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Justin Blau, Biology, 1001 Brown, 8-8261, justin.blau@nyu.edu |
Dan Sanes†, CNS, 1009 Meyer, 8-3924, sanes@cns.nyu.edu |
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Mitch Chesler, NYUSoM, cheslm01@popmail.med.nyu.edu |
Daniel Tranchina, Math & Biology, 520 Weaver, 8-3109, tranchin@cims.nyu.edu |
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Claude Desplan, Biology, 756 Brown, 8-3966, cd38@nyu.edu |
Tim Tully, Cold Spring Harbor Labs, tully@cshl.org |
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Vibhakar Kotak, CNS, 1007 Meyer, 8-3916, kotak@cns.nyu.edu |
Edward Ziff, NYUSoM, edward.ziff@med.nyu.edu |
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Margaret Rice, NYUSoM, margaret.rice@nyu.edu |
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†Course Director |
TEXTS
Gordon L. Fain, Molecular and Cellular
Physiology of Neurons, Cambridge, MA:
Harvard University Press, 1999.
Bertil Hille, Ion Channels of Excitable
Membranes, Third Edition. Sutherland,
MA: Sinauer Associates, 2001
R.S. Feldman, J.S. Meyer and L.F. Quenzer, Principles
of Neuropharmacology, Sunderland, MA:
Sinauer, 1997.
D.H. Sanes, T.A. Reh and W.A. Harris, Development
of the Nervous System, Second Edition,
Academic Press, 2005.
OTHER READINGS
(usually available as pdf or handout)
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Update: 6 December 2005
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