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Workshop on Molecular Basis of Synaptic PlasticityJune 27 - 30, 2004
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| Sunday, June 27: Welcome Dinner | |
| 7 pm | Apple Restaurant and Bar, 17 Waverly Place between Greene and Mercer St. |
| Monday, June 28: Plasticity Pathways | |
| 9-9:20 | Chiye Aoki Welcoming Remarks and Overview: What neurons can do in vivo as their neurites trespass layers and columns [ Abstracts ] |
| 9:20-10:00 | T. Iwasato Genetic Dissection of Barrel Formation in the Rodent Somatosensory System [ Abstract ] |
| 10:10-10:30 | Coffee break and discussion |
| 10:30-11:10 | Tadaharu Tsumoto Inra- and inter-neuronal trafficking of BDNF and its role in synaptogenesis [ Abstract ] |
| 11:20-12:00 | Yasunori Hayashi (MIT) Rapid and persistent modulation of actin dynamics regulates postsynaptic reorganization underlying bidirectional plasticity [ Abstract ] |
| 12:10-2:00 | Lunch break and discussion |
| 2:00-2:40 | Venki Murthy Homeostasis and the single neuron [ Abstract ] |
| 2:50-3:30 | Haruo Kasai Single-spine functions studied with two-photon photolysis of caged-glutamate [ Abstract ] |
| 3:40-4:00 | Coffee Break and discussion |
| 4:00-4:40 | Chiye Aoki The emergence of drebrin A at newly forming synapses [ Abstract ] |
| 4:50-5:30 | Dan Sanes Regulating synaptic strength during development [ Abstract ] |
| 5:30-6:00 | Discussion |
| 6:00-8:00 | Discussion over dinner Dinner for speakers and discussants and friends at Broadway Bar and Grill, on Lafayett Ave and 4th St. |
| Tuesday, June 29: Workshop theme Synaptogenesis | |
| 9-9:40 | Tomoaki Shirao Drebrin A plays a key role in cluster formation of F-actin and PSD-95 at postsynaptic site [ Abstract ] |
| 9:50-10:30 | Makoto Saji Is rat with antisense-induced in vivo knockdown of a spine protein drebrin A a model for schizophrenia? [ Abstract ] |
| 10:30-11:00 | Coffee break and discussion |
| 11:00-11:40 | Peter Scheiffele The Role of Neurexin and Neuroligin in Synaptogenesis |
| 11:50-12:30 | Shasta Sabo Trafficking of vesicle precursors towards newly forming synapses [ Abstract ] |
| 12:50-2:00 | Lunch break and discussion |
| 2:00-2:40 | Shigeo Okabe What Homer 1c, cAMP and PSD-95 do together in spines [ Abstract ] |
| 2:50-3:30 | T. Furuichi Cupidin/Homer2 regulates postsynaptic molecular organization and dendritic spine morphology [ Abstract ] |
| 3:30-4:00 | Coffee Break |
| 4:00-4:40 | Peter Penzes Regulation of dendritic spine activity-dependent structural plasticity [ Abstract ] |
| 4:50-5:30 | Shelley Halpain Actin and Membrane Regulation in Dendritic Spine Remodeling |
| 5:30-6:00 | Discussion |
| 6:00-8:30 | Dinner at Ennio and Michael's (Italian) |
| Wednesday June 30 10am - noon: Discussion over bagels and lox |
DISCUSSANTS
Kensuke Hayashi, Barbara Calabrese, Ryoki Ishikawa, Kenji Hanamura, Haruo Kasai, Masanori Matsuzaki, Yuko Sekino, William J. Tyler, Sachiko Yoshida, Chiho Kobayashi, Sho Fujisawa, Veera Mahadomrongkul, Robert Levy, Anita Disney, Gabriel Lazaro-Munoz, Yaihara Fortis-Santiago
REMARKS
Scientific questions that we could consider during the workshop throughout the two days of the workshop, we will be asking the following questions (in addition to others that will be added to the list following the speakers' arrival to the Workshop) __What are the candidate proteins involved in orchestrating the turnover of glutamate receptor subunits at synapses? (T. Tsumoto and Tomoaki Shirao) __What enzymatic activities regulate the turnover of glutamate receptor subunits at synapses or of their modification in synaptic strength? Do these enzymatic cascades cross-talk? (Peter Penzes, T. Furuichi and Shelley Halpain) __What are the roles played by different cytoskeletal proteins within spine? What is the signal transduction pathway linking receptor activation to the polymerization/depolymerization of cytoskeletal proteins? (Venkatesh Murthy, H. Kasai and Shelley Halpain)
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