Homeostasis and the single neuron

Venki Murthy

Abstract

Persistent changes in activity of individual neurons trigger adaptive responses in intrinsic excitability and synaptic transmission. By manipulating electrical activity or synaptic activity in individual neurons in an otherwise normal network, we have uncovered multiple forms of synaptic plasticity. We will discuss how these synaptic changes fit into current ideas about homeostatic and Hebbian synaptic plasticity

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